Key features and details | |
Cat. No. | MABL-1932 |
Name | Anti-IFN gamma mAbs |
Clone No. | AFD- AF2 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ICC, WB, Block, ELISA, IHC |
Species Reactivity | Human |
Basic Information | |
Specificity | The antibody binds to IFNγ with an IC50 of 65 pM and an affinity (Kd) of 19.3 nM. |
Alternative Name | Interferon gamma; Immune interferon ; IFN-gamma; IFNG |
UniProt | P01579 |
Immunogen | Human IFNγ. |
Application Notes | The antibody binds specifically to IFNγ, a dimerised soluble cytokine member of the type II class of interferons synthesised by activated T-lymphocytes and natural killer (NK) cells. . IFNγ plays a role in both the innate and adaptive immune responses |
Antibody First Published | Thakur AB, Landolfi NF.A potent neutralizing monoclonal antibody can discriminate amongst IFNγ from various primates with greater specificity than can the human IFNγ receptor complex. Mol Immunol. 1999 Oct-Nov;36(15-16):1107-15. PMID:10698312 |
Note on publication | Describes the generation of the anti-IFNγ monoclonal antibody AF2, and its ability to neutralise the activity of IFNγ in humans compared to other primates. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
