Key features and details | |
Cat. No. | MABL-1920 |
Name | Anti-ICAM3 mAbs |
Clone No. | AFD- CG106 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | FACS, IP, WB, IHC |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody recognises ICAM3 which is a ligand for the leukocyte adhesion protein LFA-1 and integrin alpha-D/beta-2. It also functions as a signaling and costimulatory molecule on T lymphocytes. |
Alternative Name | Intercellular adhesion molecule 3; ICAM-3; CDw50; ICAM-R; CD50 |
UniProt | P32942 |
Immunogen | This antibody was raised by immunising mice with fresh T cell leukaemia cells. |
Application Notes | This antibody may be used in the identification and characterisation of various leucocytes and lymphatic neoplasms. For example, one group utilised CG106 antibody to immunohistochemically stain a cryostat sample of Hodgkin's disease (Cordell et al., 1994). |
Antibody First Published | Cordell et al. Cellular distribution of human leucocyte adhesion molecule ICAM-3. J Clin Pathol. 1994 Feb;47(2):143-7. PMID:8132828 |
Note on publication | This article describes generation and characterisation of CG106 antibody. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
