Key features and details | |
Cat. No. | MABL-1901 |
Name | Anti-Human Creatine Kinase-MM mAbs |
Clone No. | AFD- MAK33 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA |
Species Reactivity | Human |
Basic Information | |
Specificity | The antibody binds specifically to the human creatine-kinase-MM subtype (and not the the MB or BB subtype). |
Alternative Name | CK-MM |
UniProt | P06732 |
Immunogen | Human creatine-kinase-MM in Al(OH)3. |
Application Notes | This antibody binds to human muscle creatine-kinase-MM, an enzyme that catalyzes the conversion of creatine and ATP to phosphocreatine and ADP, generating an ATP-buffer in the muscle. The antibody blocks CK-MM activity by 80%. |
Antibody First Published | Buckel et al. Cloning and nucleotide sequence of heavy- and light-chain cDNAs from a creatine-kinase specific monoclonal antibody Gene 1987; 51:13-19 PMID:3110009 |
Note on publication | Describes the generation of a monoclonal antibody directed against the human creatine kinase M-subunit. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
