Anti-HLA-class I mAbs

Cat. No.

MABL-1856

Name

Anti-HLA-class I mAbs

Clone No.

AFD- YTH 862.2

From

Recombinant Antibody

Isotype

Engineer antibody

Application

IP, FC, IF

Species Reactivity

Human

Basic Information

Specificity

Recognises epitope in the alpha1 domain on   the human HLA Class I heavy chain.

Alternative Name

HLA class I histocompatibility antigen; A-1   alpha chain; MHC class I antigen A*1; HLA-A; HLAA; YTH862; YTH-862

UniProt

P30443

Immunogen

phytohemagglutinin (PHA) - stimulated human   peripheral blood lymphocytes.

Application Notes

Antibody First   Published

Bindon CI, Hale G, Waldmann H. Importance of   antigen specificity for complementmediated lysis by monoclonal antibodies.   Eur J Immunol. 1988 Oct;18(10):1507-14. PMID:2973413

Note on publication

Describes the preparation of rat anti human   beta2-microglobulin antibody and characterisation of the specificities by   binding analysis, immunoprecipitation or Western blotting, furthermore   specific functional tests such as complement-mediated lysis.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.