Key features and details | |
Cat. No. | MABL-1819 |
Name | Anti-HER3 mAbs |
Clone No. | AFD- AB#3 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | functional assay, SPR, ELISA |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody binds specifically to human ErBB3. |
Alternative Name | ErBB3; Receptor tyrosine-protein kinase erbB-3; Proto-oncogene-like protein c-ErbB-3; Tyrosine kinase-type cell surface receptor HER3 |
UniProt | P21860 |
Immunogen | The original antibody was created using phage display from a human Fab-phage library. |
Application Notes | Surface plasmon resonace on the ErBB3 protein was performed with this antibody to determine the KD values (US7846440). This antibody was used for a cell binding assay. The cells used were MALME-3M cells (US7846440). The ability of this antibody to inhibit the binding of ligands to ErBB3 was tested using ADRr cells (US7846440). |
Antibody First Published | Schoeberl et al. Antibodies against ErbB3 and uses thereof. US7846440 |
Note on publication | |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |