Key features and details | |
Cat. No. | MABL-1692 |
Name | Anti-Ghrelin mAbs |
Clone No. | AFD-5611 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | SPR, ELISA |
Species Reactivity | Human |
Basic Information | |
Specificity | The antibody recognises ghrelin. The antibody binds to an epitope residing within amino acids 1-8 of desacyl ghrelin. Ghrelin is a hormone produced by enteroendocrine cells of the gastrointestinal tract, especially the stomach and is often called a "hunger hormone" because it increases the drive to eat. |
Alternative Name | GHRL; MTLRP; Appetite-regulating hormone; Growth hormone secretagogue; Growth hormone-releasing peptide; Motilin-related peptide; Protein M46 |
UniProt | Q9UBU3 |
Immunogen | The original antibody was generated by immunizing C57B16 wild-type mice with human ghrelin acylated with n-octanoic acid at the His residue at position 9. |
Application Notes | The specificity of the original format of the antibody was confirmed by ELISA analysis. The antibody preferentially binds to desacyl ghrelin compared to acylated ghrelin. The binding affinity of the Fab fragment to desacyl human ghrelin was measured by surface plasmon resonance (Kd= 0.138 nM) (US20090060920). |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
