Key features and details | |
Cat. No. | MABL-1638 |
Name | Anti-FZD7 mAbs |
Clone No. | AFD- Fab-1791 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | Blocking, in vitro, WB, FC, IHC |
Species Reactivity | Human |
Basic Information | |
Specificity | The antibody is specific for FZD7. The antibody recognises human FZD7, but not with mouse FZD7. |
Alternative Name | human frizzled receptor; Frizzled-7; Fz-7; hFz7; FzE3 |
UniProt | O75084 |
Immunogen | |
Application Notes | The antibody detected the recombinant human FZD7 by western blot analysis. The antibody reduced FZD7 signaling in breast cancer cell line MDA- B-231 about 3-fold. This antibody was used for detection of FZD7 expressed on OVCAR4 cells by flow cytometry. The antibody could block migration of a breast cancer cell line and ovarian cancer cell line OVCAR4. This antibody was used for immunohistochemistry on ovarian carcinoma and renal cell carcinoma samples (WO2016205566A1). |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
