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Anti-Ferritin H mAbs

简要描述:

This antibody binds the H subunit of human ferritin. This protein catalyzes the oxidation of ferrous iron(II) to ferric iron(III) and stores iron in a soluble, non-toxic, readily available form. Ferritin is important for iron homeostasis.

产品参数:

Cat. No.:MABL-1576

Species:Engineer

Species Reactivity:Human

Type:Recombinate

Application:IP, ELISA

详细介绍

Key features and   details


Cat. No.

MABL-1576

Name

Anti-Ferritin H mAbs

Clone No.

AFD- H107

From

Recombinant Antibody

Isotype

Engineer antibody

Application

IP, ELISA

Species Reactivity

Human

Basic Information


Specificity

This antibody binds the H subunit of human   ferritin. This protein catalyzes the oxidation of ferrous iron(II) to ferric   iron(III) and stores iron in a soluble, non-toxic, readily available form.   Ferritin is important for iron homeostasis.

Alternative Name

FTH1; FTHL6; Ferritin heavy chain; Ferritin   H subunit

UniProt

P02794

Immunogen

The original antibody was generated by immunizing BALB/c mice with human heart ferritin.

Application Notes

The binding characterization of this   antibody for H subunit of ferritin was done using ELISA and   immunoprecipitation (PMID: 3089283).

Antibody First   Published

Luzzago et al. Immunochemical characterization of human liver and heart ferritins with monoclonal   antibodies. Biochim Biophys Acta. 1986 Jul 25;872(1-2):61-71. PMID:3089283

Note on publication

Describes the generation of 27 murine   antibodies against human liver and heart ferritins.

COA Information For reference only, actual COA shall prevail

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.


 


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