Key features and details | |
Cat. No. | MABL-1472 |
Name | Anti-EGFR mAbs |
Clone No. | AFD- EGFR-8 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | inhibition, WB, ELISA |
Species Reactivity | Human |
Basic Information | |
Specificity | The antibody is specific for EGFR. |
Alternative Name | ERBB; ERBB1; HER1; PIG61; mENA; avian erythroblastic leukemia viral (v- erb-b) oncogene homolog; cell growth inhibiting protein 40; cell proliferation-inducing protein 61; proto- oncogene c-ErbB-1; receptor tyrosine-protein kinase erbB-1; epidermal growth factor receptor |
UniProt | P00533 |
Immunogen | The original antibody was generated by immunizing BALB/c female mice with head and neck squamous carcinoma cell lines, such as CA922 (Japanese Collection of Research Bioresources (JCRB), Shinjuku, Japan) and HSC4 (JCRB, Shinjuku, Japan). |
Application Notes | The humanized version of the antibody exhibited strong specific binding to both human tumor cell lines and Vero cells by flow cytometry. Experiments showed the antibody is agonistic to EGFR (US20160017053A1). |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
