Anti-DLL4 mAbs

Cat. No.

MABL-1408

Name

Anti-DLL4 mAbs

Clone No.

AFD- mh2F

From

Recombinant Antibody

Isotype

Engineer antibody

Application

in vivo, inhibition, SPR, ELISA

Species Reactivity

Human, Mouse

Basic Information

Specificity

The antibody is specific for human and mouse   DLL4.

Alternative Name

Delta-like protein 4; Drosophila Delta   homolog 4 (Delta4)

UniProt

Q9NR61

Immunogen

Application Notes

The binding affinity of the antibody to DLL4  was measured by surface plasmon resonance (Kd= 5 nM). The specificity of the   original format of the antibody for human and mouse DLL4 was confirmed by   ELISA analysis. The antibody inhibited the binding between DLL4 and the Notch   receptor, thereby inhibiting Notch signaling. The antibody was shown to   reduce the size of the tumor in mice transplanted with human lung cancer   cells A549 cells (KR1020140085790A).

Antibody First Published

Note on publication

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For   longer storage, aliquot and store at - 20⁰C.