Key features and details | |
Cat. No. | MABL-1409 |
Name | Anti-DLL4 mAbs |
Clone No. | AFD- H3L2 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | proliferation, SPR, FC |
Species Reactivity | Human |
Basic Information | |
Specificity | The antibody is specific for DLL4. |
Alternative Name | Delta4; Delta-like protein 4; Drosophila Delta homolog 4 |
UniProt | Q9NR61 |
Immunogen | The original antibody is a humanized version of the parental murine monoclonal antibody. |
Application Notes | The antibody retained the high affinity of the parental murine antibody to human DLL4 antigen (KD = 2.26 pM), as measured by SPR experiments. The humanized antibody bound to the DLL4 antigen on the surface of HUVEC cells, as shown by flow cytometry. Further, the antibody could block the inhibitory effect of DLL4 on the proliferation of HUVEC cells (CN105384819B). |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
