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Anti-CD44 mAbs

简要描述:

The antibody is specific for CD44. CD44 is a transmembrane protein belonging to a hyaladherin family. It is a hyaluronic acid receptor. The CD44 molecule is expressed in almost all the cells and tissues. However, in general, it is not expressed in the platelet, liver cell, cardiac muscle, uridiferous tubule epithelium, testis, and skin.

产品参数:

Cat. No.:MABL-963

Species:Engineer

Species Reactivity:Human

Type:Recombinate

Application:ADCC

详细介绍

Key features and details


Cat. No.

MABL-963

Name

Anti-CD44 mAbs

Clone No.

AFD- 064-003

From

Recombinant Antibody

Isotype

Engineer antibody

Application

ADCC

Species Reactivity

Human

Basic Information


Specificity

The antibody is specific for CD44. CD44 is a   transmembrane protein belonging to a hyaladherin family. It is a hyaluronic acid receptor. The CD44 molecule is expressed in almost all the cells and   tissues. However, in general, it is not expressed in the platelet, liver   cell, cardiac muscle, uridiferous tubule epithelium, testis, and skin.

Alternative Name

CDw44; CD44 antigen; Epican; Extracellular   matrix receptor III; ECMR-III; GP90 lymphocyte homing/adhesion receptor;   HUTCH-I; Heparan sulfate proteoglycan; Hermes antigen; Hyaluronate receptor;   Phagocytic glycoprotein 1; PGP-1; Phagocytic glycoprotein I; PGP-I

UniProt

P16070

Immunogen

The original antibody was isolated by   panning a phage display library against CD44.

Application Notes

The IgG1 format of the antibody specifically   bound to the cancer cells expressing CD- 44 (PC-14) and expresses the ADCC   activity (US9388249B2).

Antibody First Published


Note on publication


COA Information For reference only, actual COA shall prevail

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For   longer storage, aliquot and store at - 20⁰C.


 


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