Key features and details | |
Cat. No. | MABL-963 |
Name | Anti-CD44 mAbs |
Clone No. | AFD- 064-003 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ADCC |
Species Reactivity | Human |
Basic Information | |
Specificity | The antibody is specific for CD44. CD44 is a transmembrane protein belonging to a hyaladherin family. It is a hyaluronic acid receptor. The CD44 molecule is expressed in almost all the cells and tissues. However, in general, it is not expressed in the platelet, liver cell, cardiac muscle, uridiferous tubule epithelium, testis, and skin. |
Alternative Name | CDw44; CD44 antigen; Epican; Extracellular matrix receptor III; ECMR-III; GP90 lymphocyte homing/adhesion receptor; HUTCH-I; Heparan sulfate proteoglycan; Hermes antigen; Hyaluronate receptor; Phagocytic glycoprotein 1; PGP-1; Phagocytic glycoprotein I; PGP-I |
UniProt | P16070 |
Immunogen | The original antibody was isolated by panning a phage display library against CD44. |
Application Notes | The IgG1 format of the antibody specifically bound to the cancer cells expressing CD- 44 (PC-14) and expresses the ADCC activity (US9388249B2). |
Antibody First Published | |
Note on publication | |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |