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Anti-CD32 mAbs

简要描述:

Binds specifically to human CD32.

产品参数:

Cat. No.:MABL-880

Species:Engineer

Species Reactivity:Human

Type:Recombinate

Application:FC

详细介绍

Key features and details


Cat. No.

MABL-880

Name

Anti-CD32 mAbs

Clone No.

AFD- AT10

From

Recombinant Antibody

Isotype

Engineer antibody

Application

FC

Species Reactivity

Human

Basic Information


Specificity

 Binds specifically to human CD32.

Alternative Name

 FcgRIIb; Low affinity immunoglobulin gamma   Fc region receptor II-b; FCGR2B

UniProt

 P31994

Immunogen

 Human CD32.

Application Notes

 The antibody binds to CD32, a surface   receptor protein with a low affinity for IgG antibodies.

Antibody First Published

Greenman et al. Characterization of a new   monoclonal anti-Fc gamma RII antibody, AT10, and its incorporation into a   bispecific F(ab’)2 derivative for recruitment of cytotoxic effectors.   Molecular Immunology PMID1835758

Note on publication

Describes the production and   characterisation of a mouse monoclonal antibody against CD32 as well as the   construction of a F(ab’2) antibody of T10 for further binding studies.

COA Information For reference only, actual COA shall prevail

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For   longer storage, aliquot and store at - 20⁰C.


 


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