Key features and details | |
Cat. No. | MABL-878 |
Name | Anti-CD31 mAbs |
Clone No. | AFD- BAG-85D10 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | IHC |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody recognises CD31 (PECAM1) which is a member of the immunoglobulin superfamily and is expressed at various circulatng cells, such as neutrophils, monocytes, platelets as well as on endothelial cells. CD31 is a cell adhesion molecule and is involved in the leukocyte transendothelial migration during inflammation. |
Alternative Name | PECAM1; Platelet endothelial cell adhesion molecule; PECAM-1; EndoCAM; GPIIA'; PECA1; JC/70A; BAG 85D10 |
UniProt | P16284 |
Immunogen | This antibody was raised by immunising mice with human peripheral blood lymphocytes from a patient with high numbers of gamma-delta T cells. |
Application Notes | This antibody is recommended for the detection and identification of megakaryocytes and thrombocytes. It was used to analyse megakaryocytes in the fetal hepatoblastoma tissue samples (von Schweinitz et al., 1995). |
Antibody First Published | von Schweinitz et al. Extramedullary Hematopoiesis and Intratumoral Production of Cytokines in Childhood Hepatoblastoma Pediatr Res. 1995 Oct;38(4)：555-63 PMID：8559609 |
Note on publication | This article describes the use of BAG 85D10 antibody. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
