Cat. No.
MABL-1123
Application
FC
Isotype
Engineer antibody
Species Reactivity
Monkey, Human, Rhesus Monkey, Cynomolgus Monkey
Clone No.
YTC 182.20
From
Recombinant Antibody
Specificity
This antibody recognises human CD8. CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha). CD8 is a T-cell co-receptor involved in the recognition of MHC class I molecules. It is present on cytotoxic/suppressor T lymphocytes.
Alternative Names
Leu2; CD8; CD8A; T-cell surface glycoprotein CD8 alpha chain; T- lymphocyte differentiation antigen T8/Leu-2; CD8a; p32; YTC182.20
UniProt
P01732
Immunogen
Rats were immunised with mouse L cells transfected with human CD8 gene. Subsequently, spleen cells from the immunised DA rat were fused with cells of the rat Y3/Ag.1.2.3 myeloma line.
Application Notes
YTC 182.20 antibody is recommended for flow cytometric analysis of CD8 positive cells. It is synergistic with Ab01038.
Antibody First Published
Jonekr et al. Reactivity of mAb specific for human CD markers with Rhesus monkey leucocytes. Leucocyte Typing IV. Oxford University Press p 1058-1063
Note on publication
The article provides background information for the YTC 182.20 antibody.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
