Cat. No.
MABL-1121
Application
FC, IF
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
RIV11
From
Recombinant Antibody
Specificity
This antibody recognizes human CD8 which is a cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha). CD8 is a T-cell co-receptor involved in the recognition of MHC class I molecules. It is present on cytotoxic/suppressor T lymphocytes.
Alternative Names
CD8; CD8A; T-cell surface glycoprotein CD8 alpha chain; T-lymphocyte differentiation antigen T8/Leu-2; CD8a; Leu2; p32
UniProt
P01732
Immunogen
This antibody was raised by immunizing mice with human peripheral lymphocytes.
Application Notes
The antibody RIV11 is recommended for the detection and analysis of CD8 via flow cytometry and immunofluorescence staining of cells and tissues.
Antibody First Published
Banchereau et al. Anti-cd8 antibodies block priming of cytotoxic effectors and lead to generation of regulatory cd8+ t cells. US20090304659A1
Note on publication
This patent describes the antibody RIV11.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
