Cat. No.
MABL-916
Application
neutralize, ELISA, FC
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
I-392
From
Recombinant Antibody
Specificity
This antibody recognizes and binds human CD39. NTPDase 1 (ectonucleoside triphosphate diphosphohydrolase, also known as CD39/ENTPD1 or vascular CD39, functions together with another enzyme, CD73 (ecto-5'- nucleosidase), to hydrolyze extracellular adenosine triphosphate (ATP) and adenosine diphosphate (ADP) to generate adenosine, which binds to adenosine receptors and inhibits T-cell and natural killer (NK)-cell responses, thereby suppressing the immune system. This protein could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Application Notes
Alternative Names
ENTPD1; NTPDase 1; Ectonucleoside triphosphate Di phosphohydrolase 1; Ecto-ATP Di phosphohydrolase 1; Ecto-ATPDase 1; Ecto-ATPase 1; Ecto-apyrase; Lymphoid cell activation antigen
UniProt
P49961
Immunogen
Application Notes
Antibody First Published
Note on publication
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
