Cat. No.
MABL-900
Application
depleting
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
G28-1
From
Recombinant Antibody
Specificity
This antibody recognises CD37, which is a cell surface protein, present mostly on mature B cells and B cell malignancies.
Alternative Names
TSPAN-26; Leukocyte antigen CD37; Tetraspanin-26; tetraspanin; Tspan- 26
UniProt
P11049
Immunogen
This antibody was raised by immunizing mice with CD37.
Application Notes
G28-1 antibody was used to deplete normal and malignant B cells (Hayden-Ledbetter, unpublishesd). This antibody and antibody fragments derived therefrom have been used in the research and trials on the generation of novel immunotherapuetic agents, alternative to anti-CD20 therpaies (rituximab) (Robak and Robak, 2014).
Antibody First Published
Ledbetter et al. Monoclonal antibodies to a new gp40-45 (CD37) B cell associated cluster group modulate B cell proliferation. LEUCOCYTE TYPING III: WHITE CELL DIFFERENTIATION ANTIGENS: 339-341; Oxford University Press, USA (1987)
Note on publication
This article decribes the generation of the G28-1 antibody.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
