Cat. No.
MABL-895
Application
IP, WB, FC, IHC-Fr
Isotype
Engineer antibody
Species Reactivity
Mouse
Clone No.
8C12
From
Recombinant Antibody
Specificity
Recognises an epitope on CD35 (CR1, 190 kDa), but not on CD21 (CR2, 145-150 kDa), which are alternative splice variants of primary Cr2 gene transcripts.
Alternative Names
CR1 ; C3BR; C4BR; CD35; KN
UniProt
P17927
Immunogen
Purified murine CR1 protein.
Application Notes
This antibody recognises murine CD35, expressed on the majority of peripheral B-cells and peritoneal macrophages and upon fMet-Leu-Phe stimulation also on
Antibody First Published
Kinoshita et al. Monoclonal antibodies to mouse complement receptor type 1 (CR1). Their use in a distribution study showing that mouse erythrocytes and platelets are CR1-negative. J Immunol. 1988 May 1;140(9):3066-72 PMID:2966205
Note on publication
Describes the generation and characterization of this antibody.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
