Cat. No.
MABL-880
Application
FC
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
AT10
From
Recombinant Antibody
Specificity
Binds specifically to human CD32.
Alternative Names
FcgRIIb; Low affinity immunoglobulin gamma Fc region receptor II-b; FCGR2B
UniProt
P31994
Immunogen
Human CD32.
Application Notes
The antibody binds to CD32, a surface receptor protein with a low affinity for IgG antibodies.
Antibody First Published
Greenman et al. Characterization of a new monoclonal anti-Fc gamma RII antibody, AT10, and its incorporation into a bispecific F(ab’)2 derivative for recruitment of cytotoxic effectors. Molecular Immunology PMID：1835758
Note on publication
Describes the production and characterisation of a mouse monoclonal antibody against CD32 as well as the construction of a F(ab’2) antibody of T10 for further binding studies.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
