Cat. No.
MABL-878
Application
IHC
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
BAG-85D10
From
Recombinant Antibody
Specificity
This antibody recognises CD31 (PECAM1) which is a member of the immunoglobulin superfamily and is expressed at various circulatng cells, such as neutrophils, monocytes, platelets as well as on endothelial cells. CD31 is a cell adhesion molecule and is involved in the leukocyte transendothelial migration during inflammation.
Alternative Names
PECAM1; Platelet endothelial cell adhesion molecule; PECAM-1; EndoCAM; GPIIA'; PECA1; JC/70A; BAG 85D10
UniProt
P16284
Immunogen
This antibody was raised by immunising mice with human peripheral blood lymphocytes from a patient with high numbers of gamma-delta T cells.
Application Notes
This antibody is recommended for the detection and identification of megakaryocytes and thrombocytes. It was used to analyse megakaryocytes in the fetal hepatoblastoma tissue samples (von Schweinitz et al., 1995).
Antibody First Published
von Schweinitz et al. Extramedullary Hematopoiesis and Intratumoral Production of Cytokines in Childhood Hepatoblastoma Pediatr Res. 1995 Oct;38(4)：555-63 PMID：8559609
Note on publication
This article describes the use of BAG 85D10 antibody.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
