Cat. No.
MABL-801
Application
IP, WB, IHC
Isotype
Engineer antibody
Species Reactivity
Mouse
Clone No.
2F8 (recombinant version)
From
Recombinant Antibody
Specificity
This antibody specifically recognizes CD204, also known as the the murine scavenger receptor class A (SRA), type I and II. which is expressed by tissue macrophages and functions both as an endocytic receptor for lipoproteins and as an adhesion receptor for macrophages binding to ligand rich tissues e.g. atherosclerotic lesions.
Alternative Names
Macrophage scavenger receptor; Murine scavenger receptor class A; Macrophage scavenger receptor types I and II; Macrophage acetylated LDL receptor I and II; Scavenger receptor type A; SR-A
UniProt
P30204
Immunogen
Rats immunised with Raw 264 cell line.
Application Notes
Antibody First Published
Fraser I, Hughes D, Gordon S. Divalent cation-independent macrophage adhesion inhibited by monoclonal antibody to murine scavenger receptor. This antibody has been shown to be endocytic. Nature. 1993 Jul 22;364(6435)：343-6. PMID：8332192
Note on publication
Describes the making of 2F8 monoclonal antibody and used for characterization of macrophage adhesion.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
