Cat. No.
MABL-766
Application
IP, ELISA, FC, IHC
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
CBT6
From
Recombinant Antibody
Specificity
The antibody is specific for the human CD1a protein.
Alternative Names
T6/Leu6; T-cell surface antigen T6/Leu-6; T6; Leu 6; hTa1 thymocyte antigen; FCB6; R4; hTa1 thymocyte antigen
UniProt
P06126
Immunogen
This antibody was raised by immunizing mice with the human CD1a protein.
Application Notes
The antibody can be used to inhibit Sag-induced proliferation of MHC class II thymocytes (Gregory. et al, 2000). It can increase intracellular calcium concentration in MHC class II thymocytes if used toghether with rabbit anti-mouse antibodies (Gregory. et al, 2000). This antibody is shown to be useful in flow cytometry (Gregory. et al, 2000). Immunofluorescence is a method for which this antibody can also be used (Brocks. et al, 2017). The antibody can be utilized in immunihistochemistry to seperate human cells from cells of other animals (Goan. et al, 2000). The antibody is also reccomended for use in ELISA and immunoprecipitation.
Antibody First Published
Gregory. et al Role of the CD1a molecule in the superantigen-induced activation of MHC class II negative human thymocytes Hum Immunol. 2000 May;61(5):427-37.PMID:10773345
Note on publication
It describes the use of the antibody in inhibiting the proliferation of MHC class II thymocytes.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
