Cat. No.
MABL-761
Application
therapeutics
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
CAT-13.1E10
From
Recombinant Antibody
Specificity
CAT 13.1E10 antibody recognises CD19, which is a transmembrane glycoprotein that regulates B lymphocyte development, activation, and differentiation.
Alternative Names
Leu12; B-lymphocyte antigen CD19; B-lymphocyte surface antigen B4; Differentiation antigen CD19 T-cell surface antigen Leu-12; CD19; B4; CAT 13.1E10
UniProt
P15391
Immunogen
This antibody was raised by immunising mice against CD19.
Application Notes
This antibody is recommended for targeting and analysis of B cells. CAT-13.1E10 was used as a part of a fusion molecule aimed at intracellular delivery of BINDI in order to establish a potential treatment method of EBV-positive B lymphoma in a xenograft mouse model (US20160376333A1).
Antibody First Published
Procko et al. University of Washington, 2017. Polypeptides to inhibit epstein barr viral protein BHRF1 and B cell lymphoma family proteins. U.S. Patent 9,750,814.
Note on publication
This patent describes the potential therapeurical use of CAT-13.1E10 antibody.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
