Cat. No.
MABL-694
Application
IP, FC, IHC
Isotype
Engineer antibody
Species Reactivity
Rat
Clone No.
OX-42
From
Recombinant Antibody
Specificity
This antibody recognizes rat CD11c, the receptor for iC3 strongly expressed on macrophages.
Alternative Names
iC3b receptor; Integrin alpha X; complement component 3 receptor 4 subunit; ITGAX
UniProt
Immunogen
Resident peritoneal cells from F1 hybrids between PVG-RT1c and PVG-RTu and between PVG- RT1c and DA-RT1a rats.
Application Notes
The binding of this antibody does not interfere with phagocytosis.
Antibody First Published
Robinson, White, Mason Macrophage heterogeneity in the rat as delineated by two monoclonal antibodies MRC OX-41 and MRC OX-42, the latter recognizing complement receptor type 3. 1986 Immunology 57:239 PMID:3512425
Note on publication
Describes the generation and characterisation of this antibody.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
