Cat. No.
MABL-675
Application
FC
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
YTH 81.5
From
Recombinant Antibody
Specificity
Recognizes a 180kD glycoprotein, CD11 alpha, expressed by human leukocytes, involved in cellular adhesion and costimulatory signaling. It is the target of the drug efalizumab.
Alternative Names
CD11A; CD11a; Integrin alpha L; Integrin alpha-L; Integrin αL; ITGAL; LFA alpha-1; YTH81; YTH-81
UniProt
P20701
Immunogen
CD11 alpha/ Integrin alpha -L glycoprotein expressed in human lymphocytes.
Application Notes
Antibody First Published
Clark M, Hale G, Waldmann H. Interaction of rat monoclonal antibodies with human killer cells. Adv Exp Med Biol. 1985;186:797-803 PMID:4050599
Note on publication
Describes the preparation of rat anti human CD11 alpha antibody and characterisation of the specificities.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
