Cat. No.
MABL-668
Application
Isotype
Engineer antibody
Species Reactivity
Mouse
Clone No.
YDBYT 280.2
From
Recombinant Antibody
Specificity
This antibody recognizes murine CD103 (Integrin alpha-E). Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers. Mice expressing a null mutation of the alpha-E subunit gene exhibit a marked reduction in the numbers of intraepithelial lymphocytes in the gut and in the development of gut-associated lymphoid aggregates, supporting a specific role for this integrin in mediating retention of lymphocytes in the intestinal wall (Uniprot).
Alternative Names
Integrin alpha-E; Integrin alpha M290
UniProt
Q60677
Immunogen
The original version of this antibody was raised against murine CD103.
Application Notes
This antibody is recommended for the detection of murine CD103 ((Integrin alpha-E).
Antibody First Published
Note on publication
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
