Key features and details | |
Cat. No. | MABL-801 |
Name | Anti-CD204 mAbs |
Clone No. | AFD- 2F8 (recombinant version) |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | IP, WB, IHC |
Species Reactivity | Mouse |
Basic Information | |
Specificity | This antibody specifically recognizes CD204, also known as the the murine scavenger receptor class A (SRA), type I and II. which is expressed by tissue macrophages and functions both as an endocytic receptor for lipoproteins and as an adhesion receptor for macrophages binding to ligand rich tissues e.g. atherosclerotic lesions. |
Alternative Name | Macrophage scavenger receptor; Murine scavenger receptor class A; Macrophage scavenger receptor types I and II; Macrophage acetylated LDL receptor I and II; Scavenger receptor type A; SR-A |
UniProt | P30204 |
Immunogen | Rats immunised with Raw 264 cell line. |
Application Notes | |
Antibody First Published | Fraser I, Hughes D, Gordon S. Divalent cation-independent macrophage adhesion inhibited by monoclonal antibody to murine scavenger receptor. This antibody has been shown to be endocytic. Nature. 1993 Jul 22;364(6435)：343-6. PMID：8332192 |
Note on publication | Describes the making of 2F8 monoclonal antibody and used for characterization of macrophage adhesion. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
