Cat. No.
MABL-387
Application
ELISA
Isotype
Engineer antibody
Species Reactivity
Latrodectus tredecimguttatus (Mediterranean black widow spider)
Clone No.
TPL0020_02_G9
From
Recombinant Antibody
Specificity
TPL0029_02_G9 antibody recognizes alpha-Latrotoxin from the venom of Latrodectus tredecimguttatus (Mediterranean black widow spider).
Alternative Names
α-latrotoxin; Alpha-latrotoxin-Lt1a; Alpha-LTX-Lt1a; Alpha-LTX;latrotoxin; Latrodectus mactans tredecimguttatus
UniProt
P23631
Immunogen
Single chain variable fragment (scFv)-displaying phages from the IONTAS phage library λ with a phage diversity of 1.6・10^10 were used to select scFvs, which bind biotinylated α-latrotoxin from the Mediterranean black widow spider (L. tredecimguttatus). Three rounds of selections were performed to enrich the pool of phages with high affinity to the toxin.
Application Notes
TPL0029_02_G9 antibody was demonstrated to have high affinity towards the alpha-Latrotoxin from the venom of Latrodectus tredecimguttatus (Mediterranean black widow spider) via ELISA.This antibody is recommended for the research on the antitoxin against Latrodectus tredecimguttatus spider bites.
Antibody First Published
Føns et al. Discovery of human antibody fragments against spider venom toxins. 10.13140/RG.2.2.21155.71202. PMID
Note on publication
This poster describes the generation and characterization of the TPL0029_02_G9 antibody, as a potential treatment for Latrodectus tredecimguttatus spider bites.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
