Cat. No.
MABL-377
Application
ELISA
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
0325-6-9
From
Recombinant Antibody
Specificity
This antibody binds human alpha-fetoprotein (AFP). AFP is made in the liver of developing babies. It binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. AFP levels in healthy adults is very low. Elevated levels of AFP in adult human blood is a marker for cancer.
Alternative Names
AFP; Alpha-fetoglobulin
UniProt
P02771
Immunogen
The original antibody was generated by immunizing mice with human alpha-fetoprotein.
Application Notes
The specificity of this antibody towards hepatoma cells was determined using ELISA. The tumor targeting ability of the antibody was characterized using cell immunostaining and complement :killings assays (PMID: 1379974).
Antibody First Published
Hong et al. Characterization and nucleotide sequences of the variable regions of a monoclonal antibody against alpha-fetoprotein. Hybridoma. 1992 Jun;11(3):339-50.PMID:1379974
Note on publication
Describes the generation and characterization of this antibody.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
