Cat. No.
MABL-334
Application
Blocking, ELISA
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
Ig2838
From
Recombinant Antibody
Specificity
This antibody binds specifically to the human A2 adenosine receptor.
Alternative Names
ADORA2A
UniProt
P29274
Immunogen
Human recombinant A2-adenosine receptor.
Application Notes
This antibody binds to the A2 adenosine receptor, a G-protein-coupled receptor for adenosine that, upon ligand binding, activates adenylyl cyclase. The antibody acts as an allosteric inhibitor.
Antibody First Published
Hino et al. G-protein coupled receptor inactivation by an allosteric inverse_x0002_agonist antibody. Nature 2012; 482(7384):237-240 PMID:22286059
Note on publication
Describes the generation of an anti-adenosine receptor antibody and crystallization for structure determination.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
