Key features and details | |
Cat. No. | MABL-754 |
Name | Anti-CD18 mAbs |
Clone No. | AFD- YTS 213.1 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | IP, FC, IF, IHC-Fr |
Species Reactivity | Mouse |
Basic Information | |
Specificity | Recognises CD18 beta subunit of LFA-1 family. |
Alternative Name | Integrin beta-2; Cell surface adhesion glycoproteins LFA-1/CR3/p150;95 subunit beta; Complement receptor C3 subunit beta; Itgb2; MAC-1; YTS213; YTS-213 |
UniProt | P11835 |
Immunogen | Mouse spleen cells. |
Application Notes | This antibody recognizes murine CD18, which together with CD11b forms the complement receptor 3, also called the Macrophage 1 antigen MAC1. This antibody may be used in flow cytometry, IHC , IF and IP. The original rat IgG2a format was not known to block function. |
Antibody First Published | McDole et al. Rapid formation of extended processes and engagement of Theiler's virus-infected neurons by CNS-infiltrating CD8 T cells. Am J Pathol. 2010 Oct;177(4):1823-33.PMID:20813972 |
Note on publication | Describes the use of this antibody in IHC and IF. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
