Key features and details | |
Cat. No. | MABL-687 |
Name | Anti-CD11b mAbs |
Clone No. | AFD- 5C6 (recombinant version) |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | IF, IHC-Fr |
Species Reactivity | Mouse and Human |
Basic Information | |
Specificity | This antibody specifically recognize CD11b, also known as the integrin alpha M chain (MAC-1), which is a differentiation antigen expressed by granulocytes, monocytes, NK cells and tissue macrophages. |
Alternative Name | integrin alpha M; CD11 antigen-like family member B; CR-3 alpha chain; Cell surface glycoprotein MAC-1 subunit alpha; Leukocyte adhesion receptor MO1; Neutrophil adherence receptor |
UniProt | P11215 |
Immunogen | Fusion of spleen cells from AO rats immunised with Thioglycollate-elicted muine peritoneal macrophages (TPM) and the Y3 rat myeloma line. |
Application Notes | |
Antibody First Published | Rosen H, Gordon S. Monoclonal antibody to the murine type 3 complement receptor inhibits adhesion of myelomonocytic cells in vitro and inflammatory cell recruitment in vivo and can thereby potentiate infection. J Exp Med. 1987 Dec 1;166(6):1685-701. PMID:2445894 |
Note on publication | Describes the isolation of 5C6 and analysis of Mg2+-dependent macrophage adhesion. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
