Key features and details | |
Cat. No. | MABL-200 |
Name | Anti-Neuroligin-4 mAbs |
Clone No. | AFD-N98/7R |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ICC, WB |
Species Reactivi | Mouse |
Basic Information | |
Specificity | This antibody is specific for neuroligin-4*. Neuroligin-4* is a cell surface protein involved in cell- cell-interactions. Plays a role in the formation or maintenance of synaptic junctions via its interactions (via the extracellular domains) with neurexin family members. Plays a role in synaptic signal transmission. |
Alternative Name | Neuroligin 4-like; Nlgn4l; Neuroligin-4; NL-4; N98/7 |
UniProt | B0F2B4 |
Immunogen | This antibody was raised against a fusion protein of amino acids 782-945 of mouse Neuroligin-4*. |
Application Notes | This antibody is recommended for detection and analysis of neuroligin-4 by immunocytochemistry and western blot. For instance, the mouse version of this antibody was used to detect neuroligin-4 by western blot in extracts of MBM and COS cells transiently transfected with Neuroligin- 1 and Neuroligin-4 plasmids. |
Antibody First Published | Andrews et al. A toolbox of IgG subclass-switched recombinant monoclonal antibodies for enhanced multiplex immunolabeling of brain eLife. 2019; 8: e43322. PMID:30667360 |
Note on publication | Describes the generation of a library of recombinant monoclonal antibodies (R- mAbs) from a pool of mAb-producing hybridomas for neuroscience research. |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |