Key features and details | |
Cat. No. | MABL-133 |
Name | Anti-Dopamine D3 receptor mAbs |
Clone No. | AFD-N331/19 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ICC, IHC |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody is specific for the dopamine D3 receptor protein. Dopamine receptor whose activity is mediated by G proteins which inhibit adenylyl cyclase. Promotes cell proliferation. |
Alternative Name | N331/19R; D(3) dopamine receptor; DRD3; |
UniProt | P35462 |
Immunogen | This antibody was raised by immunising BALB/c mice with a fusion protein amino acids 223- 322 (third intracellular loop) of human Dopamine D3 receptor. |
Application Notes | This antibody is recommended for detection and analysis of Dopamine D3 receptor by immunocytochemistry. For instance, the mouse version of this antibody was used to detect dopamine D3 receptor by immunocytochemistry in COS cells expressing untagged human Dopamine D3 receptor with GFP. |
Antibody First Published | Andrews et al. A toolbox of IgG subclass-switched recombinant monoclonal antibodies for enhanced multiplex immunolabeling of brain eLife. 2019; 8: e43322. PMID:30667360 |
Note on publication | This article describes the generation of a library of recombinant monoclonal antibodies (R-mAbs) from a pool of mAb-producing hybridomas for neuroscience research. |
COA Information (For reference only, actual COA shall prevail) | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |