Key features and details | |
Cat. No. | MABL-122 |
Name | Anti-TRPML3/Mucolipin-3 mAbs |
Clone No. | AFD-N268/19 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | WB |
Species Reactivity | Rat, Human, Mouse |
Basic Information | |
Specificity | This antibody is specific for the TRPML3/Mucolipin-3 protein. TRPML3/Mucolipin-3 is a nonselective ligand-gated cation channel probably playing a role in the regulation of membrane trafficking events. |
Alternative Name | N268/19R; Mucolipin-3; Transient receptor potential channel mucolipin 3; TRPML3 |
UniProt | Q8TDD5 |
Immunogen | This antibody was raised by immunising BALB/c mice with a synthetic peptide amino acids 269-285 (CKDWHVSGSIQKNTHYM, extracellular N-terminus) of human TRPML3. |
Application Notes | This antibody is recommended for the detection and analysis of TRPML3 by western blot. For instance, the mouse version of this antibody was used to detect TRPML3 byu western blot in : extracts of rat brain membranes (RBM) and of COS cells transiently transfected with HA-tagged mouse and human TRPML3 (mTRPML3 and hTRPML3) or untagged Kv2.1 plasmid. |
Antibody First Published | Andrews et al. A toolbox of IgG subclass-switched recombinant monoclonal antibodies for enhanced multiplex immunolabeling of brain eLife. 2019; 8: e43322. PMID:30667360 |
Note on publication | This article describes the generation of a library of recombinant monoclonal antibodies (R-mAbs) from a pool of mAb-producing hybridomas for neuroscience research. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
