Anti-SynCAM4 mAbs

Cat. No.

MABL-121

Name

Anti-SynCAM4  mAbs

Clone No.

AFD-N244/5

From

Recombinant Antibody

Isotype

Engineer antibody

Application

WB, IF, IHC

Species Reactivity

Rat, Human, Mouse

Basic Information

Specificity

This antibody is specific for SynCAM4 and   shows no cross reaction with other SynCAMs. SynCAM is involved in the cell-cell   adhesion. Has calcium- and magnesium-independent cell-cell adhesion activity.   May have tumor-suppressor activity.

Alternative Name

N244/5R; Cell adhesion molecule 4;   Immunoglobulin superfamily member 4C; IgSF4C; Nectin-like protein 4; NECL-4;   TSLC1-like protein 2

UniProt

Q8R464

Immunogen

This antibody was raised by immunising   BALB/c mice with a fusion protein corresponding to amino acids 1-321 (signal   peptide and extracellular N-terminus) of mouse SynCAM4.

Application Notes

This antibody was used in   immunofluorescense experiments on COS-1 cell lines (Gong et al, 2016;   PMID:26644354). The antibody was used in western blotting of sciatic nerves   of mice (Saitoh et al, 2018; PMID:30357511). Immunohistochemistry was also   preformed on sciatic nerves of mice using this antibody (Saitoh et al, 2018;   PMID:30357511).

Antibody First Published

Gong et al Developing high-quality   mouse monoclonal antibodies for neuroscience research – approaches,   perspectives and opportunities N Biotechnol. 2016 Sep 25;33(5 Pt A):551-64.   PMID:26644354

Note on publication

This paper describes research on creating   antibodies for use in experiments on the mammalian brain.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.