Anti-Pan-FHF-A (Homo sapiens) mAbs

Cat. No.

MABL-119

Name

Anti-Pan-FHF-A (Homo sapiens)  mAbs

Clone No.

AFD-N235/22

From

Recombinant Antibody

Isotype

Engineer antibody

Application

 WB

Species Reactivity

 Rat, Human, Mouse

Basic Information

Specificity

This antibody is specific for pan-FHF-A. It cross-reacts   with FGF12A/FHF1A and FGF14A/FHF4A, but does not cross-react with   FGF13B/FHF2B. Pan-FHF-A is a microtubule-binding protein which directly binds   tubulin and is involved in both polymerization and stabilization of   microtubules (By similarity).

Alternative Name

 N235/22R; Fibroblast growth factor 13;   FGF13; Fibroblast growth factor homologous factor 2; FHF-2

UniProt

Q92913

Immunogen

This antibody was raised by immunising BALB/c   mice with a synthetic peptide amino acids 2- 18 (AAAIASSLIRQKRQARE) of human   FHF2A.

Application Notes

This antibody has been used in   immunocytochemistry experiments on DRG neurons from rats (Barbosa et al,   2016; PMID:27999940).

Antibody First Published

Barbosa et al FHF2 isoforms   differentially regulate Nav1.6 mediated resurgent sodium currents in dorsal   root ganglion neurons Pflugers Arch. 2017 Feb;469(2):195-212. PMID:27999940

Note on publication

This article describes the use of this   antibody is research on the neurons of rats.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For   longer storage, aliquot and store at - 20⁰C.