Anti-KChIP3 K+ channel mAbs

Cat. No.

MABL-078

Name

Anti-KChIP3 K+ channel  mAbs

Clone No.

AFD-K66/38

From

Recombinant Antibody

Isotype

Engineer antibody

Application

 IB, IP, IHC

Species Reactivity

 Rat, Human, Mouse

Basic Information

Specificity

This antibody is specific for KChIP3. It does not react with KChIP1, KChIP2 or KChIP4.

Alternative Name

K66/38R; Kv channel-interacting protein 3; Kcnip3, A-type potassium channel modulatory protein 3; Calsenilin; Csen; DRE- antagonist modulator; Dream

UniProt

Q9JM47

Immunogen

This antibody was raised by immunising BALB/c mice with a fusion protein containing full- length rat KChIP3.

Application Notes

This antibody has been used in immunoblot analysis of adult rat and mouse brain membranes (Andrews et al, 2019; PMID:30667360). It has also been used in immunohistochemical analysis   of KChIP3 expression in adult rat brain sections (Andrews et al, 2019; PMID:30667360) and mouse hippocampus sections (Menegola et al, 2012). Additionally, this antibody has been used to assess KChIP3 surface expression by rat primary neurons and HiB5 cells transfected to express KChIP isoforms (Pruunsild et al, 2012).

Antibody First Published

Shibata et al. A Fundamental Role   for KChIPs in Determining the Molecular Properties and Trafficking of Kv4.2 Potassium Channels J Biol Chem. 2003;278(38):36445‐36454.PMID:12829703

Note on publication

Describes the original generation of   this antibody.

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity purified

Buffer

PBS with 0.02% Proclin 300.

Concentration

1 mg/ml.

Storage Recommendation

Store at 4⁰C for up to 3 months. For   longer storage, aliquot and store at - 20⁰C.