Cat. No.
MABL-3737
Application
Block, ELISA, FC, IF
Isotype
Engineer antibody
Species Reactivity
Mouse
Clone No.
TAN 1-7
From
Recombinant Antibody
Specificity
This antibody binds to mouse CD70.
Alternative Names
TNFRS7; Tumor Necrosis Factor Ligand Superfamily Member 7; CD27 Ligand; CD27LG; TNFSF7; CD27L; Tumor Necrosis Factor Ligand 8A; Surface Antigen CD70; Ki-24 Antigen; CD70 Antigen; TNLG8A; TAN1-7; TAN17
UniProt
Q05A52
Immunogen
Recombinant mouse CD70 (extracellular domain, aa residues 41-195).
Application Notes
This antibody can be used to detect mouse CD70, the ligand for CD27. The original rat IgG1 format has been used in vivo to inhibit CD70-CD27 mediated induction of interferon gamma following injection of glycolipid activators .
Antibody First Published
Arora et al. A single subset of dendritic cells controls the cytokine bias of natural killer T cell responses to diverse glycolipid antigens. Immunity. 2014 Jan 16;40(1):105-16 PMID:24412610
Note on publication
Describes the generation and initial characterisation of this antibody and its use in vivo.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
