Cat. No.
MABL-3725
Application
FC, IHC, Imaging
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
B72.3 (Satumomab)
From
Recombinant Antibody
Specificity
Recognises human Tumor associated glycoprotein 72.
Alternative Names
TAG-72
UniProt
Immunogen
Tumour-associated glycoprotein 72 is a glycoprotein found on the surface of many cancer cells, including ovary, breast, colon, and pancreatic cells.
Application Notes
A In-111-labeled, murine version of this antibody was used in immunoscintigraphy to detect colorectal cancers in patients. In 16 % of patients, human-anti-mouse-responses developed.
Antibody First Published
Abdel-Nabi et al. In-111-labeled monoclonal antibody immunoscintigraphy in colorectal carcinoma: safety, sensitivity, and preliminary clinical results. Radiology PMID:2315476
Note on publication
Describes the use of this antibody in detection of colorectal cancers.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
