Cat. No.
MABL-3692
Application
Cytotoxicity Assay, IHC-P, in vivo, WB, ELISA, FC, IHC-Fr
Isotype
Engineer antibody
Species Reactivity
Human, Rhesus Monkey, Cynomolgus Monkey
Clone No.
YTH 34.5-G2b (Campath-1G)
From
Recombinant Antibody
Specificity
Human CD52 antigen, also known as CAMPATH-1. CD52 is expressed at high density by lymphocytes, monocytes, eosinophils, thymocytes and macrophages. It is expressed by most lymphoid derived malignancies, although expression on myeloma cells is variable.
Alternative Names
CDw52; Cambridge pathology 1 antigen; Epididymal secretory protein E5; Human epididymis-specific protein 5
UniProt
P31358
Immunogen
Human peripheral mononuclear cells enriched for T-cells.
Application Notes
Antibody First Published
Hale G et al. Removal of T cells from bone marrow for transplantation: a monoclonal antilymphocyte antibody that fixes human complement. Blood. 1983 Oct;62(4):873-82.PMID:6349718
Note on publication
Describes the generation and characterization of this antibody, including its T-cell depleting function.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
