Cat. No.
MABL-3981
Application
IP, therapeutic, IHC
Isotype
Engineer antibody
Species Reactivity
Human
Clone No.
CTM01
From
Recombinant Antibody
Specificity
This antibody is specific for the glycoprotein polymorphic epithelial mucin (MUC1), expression of which is elevated in a broad range of solid tumours of epithelial origin.
Alternative Names
MUC1; 7F11C7; PEM; CT-M-01; Mucin-1; MUC-1; Breast carcinoma- associated antigen DF3; Cancer antigen 15-3; CA 15-3; Carcinoma-associated mucin; Episialin; H23AG; Krebs von den Lungen-6; KL-6; PEMT; Peanut-reactive urinary mucin; PUM; Polymorphic epithelial
UniProt
P15941
Immunogen
Purified Seminal PSA.
Application Notes
This antibody binds to human prostate-specific antigen, which hydrolyzes semenogelin-1 triggering the liquifaction of the seminal coagulum. The antibody enhances enzymatic activity by stabilisng the open and active conformation.
Antibody First Published
Ménez et al. Crystal structure of a ternary complex between human prostate-specific antigen, its substrate acyl intermediate and an activating antibody. Journal of Molecular Biology 2008; 376(4):1021-1033 PMID:18187150
Note on publication
Describes the crystallisation of a new monoclonal antibody in complex with human PSA.
Size
100 μg Purified antibody.
Concentration
1 mg/ml.
Purification
Protein A affinity purified
Buffer
PBS with 0.02% Proclin 300.
Storage Recommendation
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C.
