Anti-CD200R [OX131](MABL-3470)

Cat. No.

MABL-3470

Name

Anti-CD200R [OX131](MABL-3470)

Clone No.

OX131

From

Recombinant Antibody

Isotype

Engineer antibody

Application

FC

Species Reactivity

Mouse

Basic Information

Specificity

Mouse CD200R, an inhibitory receptor which   is expressed on various leukocytes and delivers inhibitory signals upon   engagement with its ligand CD200R1 and CD200R2.

Alternative Name

CD200 Receptor; CD200 Cell surface   glycoprotein receptor; Cell surface glycoprotein OX2 receptor 1; CD200R1; CD200R; OX2R; CD200 receptor-like 2; HuCD200R2; CD200RLa

UniProt

Q9ES57

Immunogen

Recombinant protein consisting of the extracellular regions of CD200R and CD200RLc together with rCD4d3+4 and attachment to streptavidin coated beads.

Application Notes

Antibody First   Published

Akkaya M, Aknin ML, Akkaya B, Barclay AN. Dissection of agonistic and blocking effects of CD200 receptor antibodies.  PLoS One. 2013 May 14;8(5):e63325. PMID: 23691022

Note on publication

Describes the generation of the antibody,  shows it blocks CD200/CD200R interaction by binding to CD200R (Uniprot   Accession No. Q9ES57; Q9ES57.1).

COA Information （For reference only, actual COA shall prevail）

Size

100 μg Purified   antibody.

Concentration

1 mg/ml.

Purification

Protein A affinity   purified

Buffer

PBS with 0.02% Proclin   300.

Concentration

1 mg/ml.

Storage   Recommendation

Store at 4⁰C for up to 3   months. For longer storage, aliquot and store at - 20⁰C.