Name
PDAP1 Human
Cat. No.
MAG-6457
Tag/Conjugates
His
Source
Escherichia Coli.
Shipped
Shipped with Ice Packs
Description
PDAP1 Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 189 amino acids (1-181 a.a.) and having a molecular mass of 21.7 kDa. The PDAP1 is fused to an 8 amino acid His-Tag at C-terminus and purified by proprietary chromatographic techniques.
Synonyms
PAP1, HASPP28.
Introduction
PDAP1, increases PDGFA-stimulated cell growth in fibroblasts, however inhibits the mitogenic effect of PDGFB. PDAP1 expression is induced by TNF-alpha, and cells overexpressing PDAP1 show significantly less apoptosis on exposure to TNF-alpha.
Physical Appearance
Sterile filtered colorless solution.
Formulation
The PDAP1 solution (1mg/ml) contains 20mM Tris-HCl pH-8, 2mM DTT, 0.1M NaCl, 0.1mM PMSF & 20% glycerol.
Stability
Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
Purity
Greater than 90.0% as determined by SDS-PAGE.
Amino acid sequence
MPKGGRKGGH KGRARQYTSP EEIDAQLQAE KQKAREEEEQ KEGGDGAAGD PKKEKKSLDS DESEDEEDDY QQKRKGVEGL IDIENPNRVA QTTKKVTQLD LDGPKELSRR EREEIEKQKA KERYMKMHLA GKTEQAKADL ARLAIIRKQR EEAARKKEEE RKAKDDATLS GKRMQSLSLN K LEHHHHHH .
Safety Data Sheet
SDS
Usage
Mabioway's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
