Key features and details | |
Cat. No. | MABL-648 |
Name | Anti-CCP mAbs |
Clone No. | AFD- AbAb01-CCP |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody can detect cyclic citrullinated peptide (CCP), which is a serological marker for rheumatoid arthritis diagnosis. Citrulline is a nonstandard amino acid that is produced by diminution of arginine residue present on certain human proteins by the peptidyl arginine-deiminase (PAD) enzyme. The release of PAD from dying cells citrullinates extracellular proteins that contain arginine. Citrullination appears to be an inflammation-dependent process since it is present in many inflammatory tissues. |
Alternative Name | cyclic citrullinated peptide; |
UniProt | |
Immunogen | |
Application Notes | This antibody can be used for the detection of cyclic citrullinated peptides in a sample using ELISA (CN110272497). |
Antibody First Published | |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
