Key features and details | |
Cat. No. | MABL-505 |
Name | Anti-Beta 2 adrenergic receptor mAbs |
Clone No. | AFD- R11/E1 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | IP, WB, FC, IF |
Species Reactivity | Human |
Basic Information | |
Specificity | R11/E1 antibody recognizes human beta-2 adrenergic receptor. Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds adrenaline with far grater affinity than noradrenaline. |
Alternative Name | R11E1; Beta-2 adrenergic receptor; Beta-2 adrenoreceptor; Beta-2 adrenoceptor; β-2 adrenergic receptor; β-2 adrenoreceptor; β-2 adrenoceptor; β2AR; β2-AR |
UniProt | P07550 |
Immunogen | This antibody was raised by immunizing mice with beta-2 adrenergic receptor. |
Application Notes | This antibody is recommended for the detection and analysis of the beta-2 adrenergic receptor. It was successfully used in the in vivo phosphorylation assays during Western blot detections of beta-2 adrenergic receptor (Huang et al., 2009). |
Antibody First Published | Huang et al. A surface of the kinase domain critical for the allosteric activation of G protein-coupled receptor kinases. J Biol Chem. 2009 Jun 19;284(25):17206-15. doi: 10.1074/jbc.M809544200. Epub 2009 Apr 13. PMID:19364770 |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
