Key features and details | |
Cat. No. | MABL-485 |
Name | Anti-Basal cell Cytokeratin mAbs |
Clone No. | AFD- RCK103 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | FC, IHC |
Species Reactivity | canine, Chicken, Guinea Pig, Hamster, Quail, Rabbit, Rat, Swine, Zebrafish, Human |
Basic Information | |
Specificity | The original antibody recognizes, among others, Cytokeratin 5. Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in Human epithelial tissues by at least 20 different polypeptides. |
Alternative Name | K5; CK-5; Keratin type II cytoskeletal 5; 58 kDa cytokeratin; Cytokeratin- 5; Keratin-5; Type-II keratin Kb5 |
UniProt | P13647 |
Immunogen | The original antibody was generated by immunizing a BALB/c mouse with a mix of cell preparations containing human cytokeratins. |
Application Notes | The antibody was employed for IHC staining of keratin in tumors and normal gland reserve cells (Vos et al.,1993; PMID： 8212457). Further, the antibody could stain the basal cell compartment in human prostate (Verhagen et al., 1992; PMID： 1384957). The antibody stained basal cells of the prostatic epithelium (Verhagen et al. 1988; PMID： 2458583). |
Antibody First Published | Feitz et al. Intermediate filament proteins as tissue specific markers in normal and malignant urological tissues J Urol. 1986 Oct;136(4)：922-31. PMID：3020261 |
Note on publication | The original paper describes the generation and characterization of the antibody. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
