Key features and details | |
Cat. No. | MABL-479 |
Name | Anti-BA46 mAbs |
Clone No. | AFD- Mc3 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | Bio-distribution, RIA |
Species Reactivity | Human |
Basic Information | |
Specificity | BA46 is a glycoprotein of the human milk fat globule membrane, and is also expressed in breast carcinomas. |
Alternative Name | MFGE8 milk fat globule-EGF factor 8 protein; BA46; HMFG; MFGM; SED1; hP47; EDIL1; MFG-E8; SPAG10; OAcGD3S; HsT19888 |
UniProt | Q08431 |
Immunogen | This antibody was raised by immunising BALB/c mice with delipidated human milk fat globules. |
Application Notes | In radioimmunoassays Mc3 bound to membranes of HMFG, MCF-7, MDA-MB- 157, SKBR-3, and BT-20 cells but not breast fibroblast, Hela, HT-29, Bristol 8, Hs294T, Hs695T, Hs785T, Hs769T, A498, PANC-1, MIA PaCa-2 or A-549 cells (Ceriani et al, 1983). Human Mc3 was characterised using biodistribution studies and shown to have similar properties to the murine Mc3 (Couto et al, 1995). |
Antibody First Published | Ceriani et al. Characterization of Cell Surface Antigens of Human Mammary Epithelial Cells with Monoclonal Antibodies Prepared Against Human Milk Fat Globule Somatic Cell Genet.1983 Jul;9(4)：415-27. PMID：6353626 |
Note on publication | Describes the original generation of this antibody and its characterisation using RIA. |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
