Key features and details | |
Cat. No. | MABL-472 |
Name | Anti-B7-H3 mAbs |
Clone No. | AFD- A3 |
From | Recombinant Antibody |
Isotype | Engineer antibody |
Application | ELISA |
Species Reactivity | Human |
Basic Information | |
Specificity | This antibody binds human B7-H3, which is a type I membrane protein highly expressed in a variety of solid tumors. |
Alternative Name | CD276; B7-H3; B7H3; CD276 antigen; B7 homolog 3; 4Ig-B7-H3; costimulatory molecule |
UniProt | Q5ZPR3 |
Immunogen | The original antibody was generated by immunizing BALB/c mice with recombinant human B7-H3. |
Application Notes | This antibody binds human B7-H3 with a strong affinity of 3.16 pM. It positively binds human B7-H3 in an ELISA. This antibody was also capable of binding MDA-MB-231 cells that highly express B7-H3 (WO2018161872A1). |
Antibody First Published | WO2018161872A1 |
Note on publication | |
COA Information （For reference only, actual COA shall prevail） | |
Size | 100 μg Purified antibody. |
Concentration | 1 mg/ml. |
Purification | Protein A affinity purified |
Buffer | PBS with 0.02% Proclin 300. |
Concentration | 1 mg/ml. |
Storage Recommendation | Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at - 20⁰C. |
